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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK3
All Species:
44.55
Human Site:
Y159
Identified Species:
61.25
UniProt:
Q00526
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00526
NP_001249.1
305
35046
Y159
F
G
V
P
L
R
T
Y
T
H
E
V
V
T
L
Chimpanzee
Pan troglodytes
XP_523720
325
36841
Y179
F
G
V
P
L
R
T
Y
T
H
E
V
V
T
L
Rhesus Macaque
Macaca mulatta
XP_001102596
305
34903
Y159
F
G
V
P
L
R
T
Y
T
H
E
V
V
T
L
Dog
Lupus familis
XP_540442
303
34173
Y157
F
G
V
P
L
R
T
Y
T
H
E
V
V
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80YP0
303
33870
T158
A
F
G
V
P
L
R
T
Y
T
H
E
V
V
T
Rat
Rattus norvegicus
Q63699
298
33869
Y159
F
G
V
P
V
R
T
Y
T
H
E
V
V
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
Y160
F
G
I
P
V
R
V
Y
T
H
E
V
V
T
L
Frog
Xenopus laevis
P23437
297
33852
F159
F
G
V
P
V
R
T
F
T
H
E
V
V
T
L
Zebra Danio
Brachydanio rerio
NP_998571
298
34001
Y159
F
G
V
P
V
R
T
Y
T
H
E
V
V
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
Y160
F
G
I
P
V
R
I
Y
T
H
E
I
V
T
L
Honey Bee
Apis mellifera
XP_393450
299
34033
Y158
F
G
V
P
V
R
T
Y
T
H
E
I
V
T
L
Nematode Worm
Caenorhab. elegans
P34556
332
38277
Y178
I
G
I
P
I
R
V
Y
T
H
E
V
V
T
L
Sea Urchin
Strong. purpuratus
XP_790847
299
34142
Y159
F
G
V
P
V
R
T
Y
T
H
E
V
V
T
L
Poplar Tree
Populus trichocarpa
XP_002306004
294
33768
F147
N
A
L
K
L
A
D
F
G
L
A
R
A
F
G
Maize
Zea mays
P23111
294
33816
F147
N
A
L
K
L
A
D
F
G
L
A
R
A
F
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
F147
N
S
L
K
L
A
D
F
G
L
A
R
A
F
G
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
F155
G
N
L
K
L
G
D
F
G
L
A
R
A
F
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
96.7
88.5
N.A.
82.6
74.7
N.A.
N.A.
63.6
73.7
73.7
N.A.
62.9
67.2
58.1
69.5
Protein Similarity:
100
93.5
98.3
92.7
N.A.
91.8
84.5
N.A.
N.A.
78
84.5
83.2
N.A.
76.7
80.6
69.5
82.6
P-Site Identity:
100
100
100
100
N.A.
6.6
93.3
N.A.
N.A.
80
86.6
93.3
N.A.
73.3
86.6
73.3
93.3
P-Site Similarity:
100
100
100
100
N.A.
6.6
100
N.A.
N.A.
93.3
100
100
N.A.
93.3
100
86.6
100
Percent
Protein Identity:
65.2
64.2
N.A.
65.5
62.3
N.A.
Protein Similarity:
81.6
80.9
N.A.
81.3
77.7
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
20
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
12
0
0
0
18
0
0
0
0
24
0
24
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
71
6
0
0
0
% E
% Phe:
65
6
0
0
0
0
0
30
0
0
0
0
0
24
0
% F
% Gly:
6
71
6
0
0
6
0
0
24
0
0
0
0
0
24
% G
% His:
0
0
0
0
0
0
0
0
0
71
6
0
0
0
0
% H
% Ile:
6
0
18
0
6
0
6
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
24
0
48
6
0
0
0
24
0
0
0
0
71
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
18
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
71
6
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
71
6
0
0
0
0
24
0
0
0
% R
% Ser:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
53
6
71
6
0
0
0
71
6
% T
% Val:
0
0
53
6
42
0
12
0
0
0
0
59
77
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _